BOTOX® Cosmetic (onabotulinumtoxinA) Since the approval of BOTOX® Cosmetic by the U.S. Food and Drug Administration in 2002, Allergan has virtually changed the face of medical aesthetics. Men and women between the ages of 18 to 65 now have the ability to choose science-based, non-invasive medical aesthetic solutions, including BOTOX® Cosmetic and the JUVÉDERM® family of dermal fillers, to achieve their own results. Since its approval, BOTOX® Cosmetic has been the number-one physician-administered aesthetic procedure in the United States. BOTOX® Cosmetic is a simple, non-surgical procedure for temporarily smoothing moderate to severe glabellar lines – the vertical frown lines between the eyebrows that look like an “11″ – in adult women and men aged 18 to 65. BOTOX® Cosmetic reduces the activity of the muscles that cause the “11s” to form by blocking nerve impulses that trigger wrinkle-causing muscle contractions, creating an improved appearance between the brows. Results can last up to four months and may vary with each patient. Ask your doctor if BOTOX® Cosmetic is right for you. Indication BOTOX® Cosmetic is a prescription medicine that is injected into muscles and used to improve the look of moderate to severe frown lines between the eyebrows (glabellar lines) in adults younger than 65 years of age for a short period of time (temporary).